Explore Hotel

Conveniently located off I-95, this Santee hotel offers cozy guest rooms and easy access to area attractions, including golf courses and state parks.

Rated number one on TripAdvisor for the Town of Santee, the BEST WESTERN PLUS Santee Inn offers spacious, comfortable and well-appointed guest rooms, each ground-level room complete with parking just outside your door, cable satellite television with HBO and free high-speed Internet access. Other amenities at this Santee State Park hotel also include a complimentary deluxe continental breakfast each morning, an outdoor heated swimming pool and an on-site restaurant for grabbing a quick bite to eat.

Traveling on business? The BEST WESTERN PLUS Santee Inn is the perfect stop to rest and relax while traveling along the East Coast, and we even offer meeting facilities for a more productive stay.

While staying in town, be sure to visit local area attractions that surround this hotel in Santee, including Santee State Park, the National Wildlife Refuge, beautiful Lake Marion and more. Plus with many golf courses located just two miles away, like Santee Cooper Golf Resort and National Golf Course, if you are looking to get some time in on the fairways this is the place!

When visiting Santee, South Carolina, theres only one place to stay, the BEST WESTERN PLUS Santee Inn. Make your reservations online today to save at this spectacular hotel with a convenient location along I-95. Enjoy your stay.

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I-95 Exit 98
South Carolina
United States
AAA - 3 Diamond


Pets: No Pets accepted
Check-in & Check-out
13:00:00 | 11:00:00
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  • Free WIFI
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Rooms & Rates


Location and Attractions

Getting there.

Sat nav users: type 29142

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I-95 Exit 98
South Carolina
United States

What's nearby?


  • 15.00 mile(s) from Holley Hill

  • 20.00 mile(s) from Manning

  • 25.00 mile(s) from Orangeburg

  • 60.00 mile(s) from Charleston

Room Theatre Classroom U-Shape Boardroom Banquet
Have an enquiry?
Contact events on 0845 620 0506


  • TripAdvisor
TripAdvisor Traveller Rating: Rating: Based on 817 traveller reviews
Rating: 5 456
Rating: 4 263
Rating: 3 72
Rating: 2 13
Rating: 1 13

Another winner.

29/09/2016 Darlene B, Fort Myers

Extremely easy and smooth check in. Room was excellent, with comfortable bed and no funky smells. All rooms are open to the outside, so you can park right at your door. Awesome AD and overall pleasant... more


Best western Santee

27/09/2016 John P, Flagler Beach, United States

A very convenient location just off I95. Great Restaurant right next to hotel. Friendly staff and easy to get in and out. This is a great place to stop on your North South travels as you go up and dow... more


Reliable choice in Santee

27/09/2016 lawrence152, Hanover, Maryland

Welcoming staff and lobby after a long day on the road. Average size room with little frills but clean and comfortable. Pool area looked nice although we did not use it because of the weather. Brea... more


Large clean room

27/09/2016 804PartyOf5, Richmond, Virginia

We stopped here on our drive from Virginia to Florida. I thought it was a good value for the price. The room was large and comfortable for 5 (2 adults, 3 kids. We did prepare for one kid to sleep o... more


A lovely older motel, immaculately kept

24/09/2016 deeloves2travel, Philadelphia, Pennsylvania

We have been stopping in Santee, South Carolina, on our annual trek down to Florida from Philly and have tried to book a room here, but they have always been full. Now I see why. We lucked out this ... more