Explore Hotel

Business at Bell Helicopter and Pantex are just a couple of reasons many guests choose to stay at our conveniently located Amarillo hotel.

If youre in town for the Big Texan Steak Ranch, its just a short drive away from our hotel in Amarillo, TX. Whether youre here for business or leisure, depend on us to provide you with the southern hospitality you deserve. Rick Husband International Airport is nearby, only three and a half miles away, so its easy to catch an early or connecting flight. Adjoining rooms are available too, so families or groups can stay connected while on vacation.

Our pet-friendly Amarillo, TX hotel offers a free, full hot breakfast that includes waffles and cereal, yogurt, pastries, fruits and breakfast breads. Complete the most important meal of the day with cups of chilled juice or 100 Arabica coffee. The Palo Duro Canyon is nearby so to really enjoy a full day of exploration, a hearty breakfast is in order.

Spend your trip visiting Wonderland Park, the American Quarter Horse Museum or the Amarillo Zoo. Cadillac Ranch and the Route 66 Motor Speedway are also popular attractions. Golf is a popular activity in the area as well. There are endless things to do near our Amarillo hotel, so start planning your itinerary now. Our friendly staff members are happy to offer tips and recommendations on places to eat, things to do and sights to see, too.

A number of our Amarillo hotel guests are in town for business with Tyson, Bell Helicopter and Pantex. With the Amarillo Air Force Base (AFB) nearby, we also welcome service men and women along with their loved ones to our property. Our superior location makes it easy to get around town and the value and amenities are unbeatable.

Book a quiet, cool room at the BEST WESTERN Santa Fe today for an easy, stress-free trip!

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4600 I-40 E
United States
AAA - 2 Diamond


Pets: No Pets accepted
Check-in & Check-out
14:00:00 | 11:00:00
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  • Free WIFI
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Rooms & Rates


Location and Attractions

Getting there.

Sat nav users: type 79103-6200

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4600 I-40 E
United States

What's nearby?


  • 110 mile(s) from Lubbock

  • 300 mile(s) from Oklahoma City

  • 350 mile(s) from Dallas

Room Theatre Classroom U-Shape Boardroom Banquet
Have an enquiry?
Contact events on 0845 620 0506


  • TripAdvisor
TripAdvisor Traveller Rating: Rating: Based on 473 traveller reviews
Rating: 5 167
Rating: 4 160
Rating: 3 83
Rating: 2 33
Rating: 1 30

Just off I-40.

02/12/2016 Clare46408, Fort Worth, Texas

The BW Santa Fe is a place to sleep that's relatively reasonable. It's nothing fancy. The lobby decor is rather strange - very modern in grays and mauve. Our room was large and clean so no real com... more


Clean and Updated

30/11/2016 joannb55, Freedom, New Hampshire

Wanted a place to just sleep and relax after a 10 hour drive. Really happy to see a Best Western in the heart of Amarillo as they are clean and I am trying to stick with their rewards points and be a ... more


Very nicely updated

20/11/2016 nomadgirl70South, Fort Irwin, California

The hotel had been recently refurbished, and very nicely at that. Staff was very quick and efficient. It smelled nice when entering which was nice considering the place is down wind of a cattle/slaugh... more


Quiet enjoyable stay

19/11/2016 2006ranchlady, McAlister, New Mexico

We have stayed here before and like it. It is a good hotel, not fancy but always comfortable and quiet even though it is on the interstate. The beds are quite comfortable and the rooms are clean and... more


Enjoyed my stay and the staff

19/11/2016 wialliamb, Parker, Colorado

Room was very clean, beds firm and comfortable. We were traveling with a big dog and the staff treated us great. Very easy to make reservation and staff was great when we showed up at 11:30 PM at ni... more