• Low rate guarantee
  • Free WIFI
  • 250+ hotels in GB

Best Western Santa Fe

AAA - 2 Diamond

Rooms & Rates

Please select
Secure the best rate with Best Western Rewards.
Exclusive discounts always available to Rewards members. Joining is free and easy.

Explore Hotel

Business at Bell Helicopter and Pantex are just a couple of reasons many guests choose to stay at our conveniently located Amarillo hotel.

If youre in town for the Big Texan Steak Ranch, its just a short drive away from our hotel in Amarillo, TX. Whether youre here for business or leisure, depend on us to provide you with the southern hospitality you deserve. Rick Husband International Airport is nearby, only three and a half miles away, so its easy to catch an early or connecting flight. Adjoining rooms are available too, so families or groups can stay connected while on vacation.

Our pet-friendly Amarillo, TX hotel offers a free, full hot breakfast that includes waffles and cereal, yogurt, pastries, fruits and breakfast breads. Complete the most important meal of the day with cups of chilled juice or 100 Arabica coffee. The Palo Duro Canyon is nearby so to really enjoy a full day of exploration, a hearty breakfast is in order.

Spend your trip visiting Wonderland Park, the American Quarter Horse Museum or the Amarillo Zoo. Cadillac Ranch and the Route 66 Motor Speedway are also popular attractions. Golf is a popular activity in the area as well. There are endless things to do near our Amarillo hotel, so start planning your itinerary now. Our friendly staff members are happy to offer tips and recommendations on places to eat, things to do and sights to see, too.

A number of our Amarillo hotel guests are in town for business with Tyson, Bell Helicopter and Pantex. With the Amarillo Air Force Base (AFB) nearby, we also welcome service men and women along with their loved ones to our property. Our superior location makes it easy to get around town and the value and amenities are unbeatable.

Book a quiet, cool room at the Best Western Santa Fe today for an easy, stress-free trip!

View more


4600 I-40 E
United States
AAA - 2 Diamond


Pets: No Pets accepted
Check-in & Check-out
14:00:00 | 11:00:00


Location and Attractions

Getting there.

Sat nav users: type 79103-6200

Send to Tom Tom

4600 I-40 E
United States

What's nearby?


  • 110 mile(s) from Lubbock

  • 300 mile(s) from Oklahoma City

  • 350 mile(s) from Dallas

Room Theatre Classroom U-Shape Boardroom Banquet
Have an enquiry?
Contact events on 0845 620 0506


TripAdvisor Traveller Rating: Rating: Based on 641 traveller reviews
Rating: 5 250
Rating: 4 210
Rating: 3 103
Rating: 2 41
Rating: 1 37

Home Away from Home!

15/07/2018 lupe395, Dalhart, Texas

Absolutely loved staying here! My kids had so much fun at the pool. The manager, Andria, brought us warm towels straight out of the dryer. She was very accommodating and friendly! The rooms were spaci... more


Best Best Western EVER!!!

15/07/2018 Justin L,

Very friendly staff. Kids loved the pool. The rooms were amazing. Huge tv, clean comfy beds. Fully stocked restrooms. Breakfast was like home cookin! Will definitely stay here every time I come to vis... more


Amazing Staff

15/07/2018 Anthony S,

The manager Andria was amazing, super helpful for me and my service dog. Very accommodating, welcoming and just respectful. I recommend this this Best Western. Our room was top notch for cleanlines... more

Owner Response
Andria K, General Manager at Best Western Santa Fe, responded to this review
Wow! Thank you for the kind words Anthony! We were happy to serve you and your service dog! Harley was so sweet and all the guests loved him! I'm happy to hear that you enjoyed your breakfast, I will pass along your compliments to our breakfast attendants Martha & Amy! If you ever need assistance booking a room you can call us directly at 806-372-1885! We hope to see you again soon at the Best Western Santa Fe Inn!

Dog-friendly, a sight for road-weary eyes, and a wonderful bed too!!

13/07/2018 PokerStorm, Sherman, TX

We were SO pooped after driving 600 miles from Flagstaff the same day, and with an 80-pound Rottweiler it's not always easy to find a place to stay. However, this property came up on a "dog hotel sear... more

Owner Response
Andria K, General Manager at Best Western Santa Fe, responded to this review
Thank you! Your review was so eloquent and gracious, thank you. Your appreciation of the experience we want our guests to have is wonderful! We are looking forward to have you back here at the Best Western Santa Fe Inn ! If you need any assistance booking a future reservation you can call us directly at 806-372-1885!

Average stay

30/06/2018 Weaton13, Wharton, Texas

My family and I stayed one night here. Everything went smoothly and everyone was friendly. You can tell they tried to update everything but it’s already outdated, esp the lobby decor. Breakfast was ju... more

Owner Response
Andria K, General Manager at Best Western Santa Fe, responded to this review
Hello! I'm happy to hear that all of our staff here was friendly during your stay with us! I apologize that you felt the lobby décor was outdated. I do appreciate any and all feedback from our guests, it does help me implement better procedures to satisfy our guests. Once again, I would love to personally speak with you regarding your stay with us. You may reach me at 806-372-1885 or by emailing me at bestwesternsantafe@yahoo.com