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Conveniently located off I-95, this Santee hotel offers cozy guest rooms and easy access to area attractions, including golf courses and state parks.

Rated number one on TripAdvisor for the Town of Santee, the BEST WESTERN PLUS Santee Inn offers spacious, comfortable and well-appointed guest rooms, each ground-level room complete with parking just outside your door, cable satellite television with HBO and free high-speed Internet access. Other amenities at this Santee State Park hotel also include a complimentary deluxe continental breakfast each morning, an outdoor heated swimming pool and an on-site restaurant for grabbing a quick bite to eat.

Traveling on business? The BEST WESTERN PLUS Santee Inn is the perfect stop to rest and relax while traveling along the East Coast, and we even offer meeting facilities for a more productive stay.

While staying in town, be sure to visit local area attractions that surround this hotel in Santee, including Santee State Park, the National Wildlife Refuge, beautiful Lake Marion and more. Plus with many golf courses located just two miles away, like Santee Cooper Golf Resort and National Golf Course, if you are looking to get some time in on the fairways this is the place!

When visiting Santee, South Carolina, theres only one place to stay, the BEST WESTERN PLUS Santee Inn. Make your reservations online today to save at this spectacular hotel with a convenient location along I-95. Enjoy your stay.

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I-95 Exit 98
South Carolina
United States
AAA - 3 Diamond


Pets: No Pets accepted
Check-in & Check-out
13:00:00 | 11:00:00
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  • Free WIFI
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Rooms & Rates


Location and Attractions

Getting there.

Sat nav users: type 29142

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I-95 Exit 98
South Carolina
United States

What's nearby?


  • 15.00 mile(s) from Holley Hill

  • 20.00 mile(s) from Manning

  • 25.00 mile(s) from Orangeburg

  • 60.00 mile(s) from Charleston

Room Theatre Classroom U-Shape Boardroom Banquet
Have an enquiry?
Contact events on 0845 620 0506


  • TripAdvisor
TripAdvisor Traveller Rating: Rating: Based on 835 traveller reviews
Rating: 5 464
Rating: 4 270
Rating: 3 75
Rating: 2 13
Rating: 1 13

The reviews are spot-on! 5-STARS all the way!

04/12/2016 Francis H, Sarasota, Florida

I used my Hotels.com rewards for a free night after reading all the great reviews on this place because I had to travel to Myrtle. Beach. Checked in at 11-pm. Super-friendly woman working at the des... more


Great place to stay

28/11/2016 Bruce B, Ocala, Florida

We stopped here for the night. What a wonderful hotel/motel. Located off I-95 but far enough away where you heard no traffic noise. The room and the entire motel and grounds were clean and in excellen... more


Small pet-friendly rooms

27/11/2016 islandtrav07, British Virgin Islands

My son and I stayed at this property on our way south to Florida with two small dogs. I like that they do accept pets and have pet-friendly rooms. However, the beds were really small (don't believe th... more


Best Western Plus in Santee, SC

19/11/2016 BPoucher, Arlington Heights, Illinois

This one-story motel is an excellent place to spend the night.--a comfortable, clean room with an enjoyable breakfast and homey breakfast room. Supper club type restaurant is a short walk away, right... more


Once again a great place for your golf trip

18/11/2016 RCAF831, Barrie, Canada

So close to three awesome course...across the parking lot to the driving range, great amenities, and the breakfast will satisfy everyone. The beds are terrific and the room is big enough to accommoda... more