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Conveniently located off I-95, this Santee hotel offers cozy guest rooms and easy access to area attractions, including golf courses and state parks.

Rated number one on TripAdvisor for the Town of Santee, the Best Western Plus Santee Inn offers spacious, comfortable and well-appointed guest rooms, each ground-level room complete with parking just outside your door, cable satellite television with HBO and free high-speed Internet access. Other amenities at this Santee State Park hotel also include a complimentary deluxe continental breakfast each morning, an outdoor heated swimming pool and an on-site restaurant for grabbing a quick bite to eat.

Traveling on business? The Best Western Plus Santee Inn is the perfect stop to rest and relax while traveling along the East Coast, and we even offer meeting facilities for a more productive stay.

While staying in town, be sure to visit local area attractions that surround this hotel in Santee, including Santee State Park, the National Wildlife Refuge, beautiful Lake Marion and more. Plus with many golf courses located just two miles away, like Santee Cooper Golf Resort and National Golf Course, if you are looking to get some time in on the fairways this is the place!

When visiting Santee, South Carolina, theres only one place to stay, the Best Western Plus Santee Inn. Make your reservations online today to save at this spectacular hotel with a convenient location along I-95. Enjoy your stay.

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I-95 Exit 98
South Carolina
United States
AAA - 3 Diamond


Pets: No Pets accepted
Check-in & Check-out
13:00:00 | 11:00:00
  • Low rate guarantee
  • Free WIFI
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Rooms & Rates


Location and Attractions

Getting there.

Sat nav users: type 29142

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I-95 Exit 98
South Carolina
United States

What's nearby?


  • 15.00 mile(s) from Holley Hill

  • 20.00 mile(s) from Manning

  • 25.00 mile(s) from Orangeburg

  • 60.00 mile(s) from Charleston

Room Theatre Classroom U-Shape Boardroom Banquet
Have an enquiry?
Contact events on 0845 620 0506


  • TripAdvisor
TripAdvisor Traveller Rating: Rating: Based on 863 traveller reviews
Rating: 5 476
Rating: 4 281
Rating: 3 78
Rating: 2 15
Rating: 1 13

Expect Less, Get More

17/01/2017 Karen W, Jamesport, New York, United States

Never expected to like it so much based on other peoples reviews. We found this place to be quite comfortable, neat and clean. Our room was in the rear building as we had our little SHih-Tzu dog with ... more


Not as Good as Expected

17/01/2017 Kathleen P, Yardley, Pennsylvania

After reading all the reviews I was expecting something really nice. It was OK, but not a 4.6. The room was dated. The sink filled halfway up as you washed your hands and took forever to drain out. Th... more


Easy stay

17/01/2017 Joy B, Lexington

very nice would stay there again Excellent restaurant next door with wonderful service. Easy access from the interstate. Friendly check in and good breakfast service. The grounds were very beautiful a... more


a very safe bet

17/01/2017 Jack S, Canada

Best Western Plus in Santee has become our routine stop en route to Florida. Always clean, quiet and comfortable with good TV and wi fi. Restaurants nearby. Plus a driving range across the street, and... more


Great place to stay

15/01/2017 Mrs5202, Stuart, Virginia

Have stopped here several times during travels to/from Florida. Easy access from interstate. Nice clean rooms. Only criticism is they don't take pets so anyone traveling with pets will have to skip t... more