Explore Hotel

Business at Bell Helicopter and Pantex are just a couple of reasons many guests choose to stay at our conveniently located Amarillo hotel.

If youre in town for the Big Texan Steak Ranch, its just a short drive away from our hotel in Amarillo, TX. Whether youre here for business or leisure, depend on us to provide you with the southern hospitality you deserve. Rick Husband International Airport is nearby, only three and a half miles away, so its easy to catch an early or connecting flight. Adjoining rooms are available too, so families or groups can stay connected while on vacation.

Our pet-friendly Amarillo, TX hotel offers a free, full hot breakfast that includes waffles and cereal, yogurt, pastries, fruits and breakfast breads. Complete the most important meal of the day with cups of chilled juice or 100 Arabica coffee. The Palo Duro Canyon is nearby so to really enjoy a full day of exploration, a hearty breakfast is in order.

Spend your trip visiting Wonderland Park, the American Quarter Horse Museum or the Amarillo Zoo. Cadillac Ranch and the Route 66 Motor Speedway are also popular attractions. Golf is a popular activity in the area as well. There are endless things to do near our Amarillo hotel, so start planning your itinerary now. Our friendly staff members are happy to offer tips and recommendations on places to eat, things to do and sights to see, too.

A number of our Amarillo hotel guests are in town for business with Tyson, Bell Helicopter and Pantex. With the Amarillo Air Force Base (AFB) nearby, we also welcome service men and women along with their loved ones to our property. Our superior location makes it easy to get around town and the value and amenities are unbeatable.

Book a quiet, cool room at the BEST WESTERN Santa Fe today for an easy, stress-free trip!

View more


4600 I-40 E
United States
AAA - 2 Diamond


Pets: No Pets accepted
Check-in & Check-out
14:00:00 | 11:00:00
  • Low rate guarantee
  • Free WIFI
  • 270+ hotels in GB

Rooms & Rates


Location and Attractions

Getting there.

Sat nav users: type 79103-6200

Send to Tom Tom

4600 I-40 E
United States

What's nearby?


  • 110 mile(s) from Lubbock

  • 300 mile(s) from Oklahoma City

  • 350 mile(s) from Dallas

Room Theatre Classroom U-Shape Boardroom Banquet
Have an enquiry?
Contact events on 0845 620 0506


  • TripAdvisor
TripAdvisor Traveller Rating: Rating: Based on 448 traveller reviews
Rating: 5 158
Rating: 4 150
Rating: 3 78
Rating: 2 32
Rating: 1 30


29/09/2016 RichKarenDavePam, Mission Viejo, California, Usa

Overall a fine stop. Nice breakfast, clean throughout, very good bed, Free WiFi, good location. fine service, good restaurants in the area. If on the road, call by 4:30 PM for availability and prices.... more


Floor in room was very dirty.

28/09/2016 Teresa M, Tucson, United States

We hated to walk on the floor in our room it was sticky and dirty. We did tell the front desk. Everything else was fine. Not the best breakfast but okay. We would try it again if we could check the ro... more

Owner Response
Andria K, General Manager at BEST WESTERN Santa Fe, responded to this review
Teresa, I am very sorry to read this review! I apologize that we at the Best Western Santa Fe of Amarillo did not exceed your expectations. I have notified our housekeeping and maintenance department about the sticky carpet issue. I can assure you that we will get this issue resolved. I do hope that you give us another chance when you travel through the Amarillo TX area again! If you need to speak with me directly regarding this matter you may telephone me at 806-372-1885. Or you may email me at bestwesternsantafe@yahoo.com. Have a wonderful day! Andria Keelin

Where In the World Is The Best Western

27/09/2016 Ken A, Martinsville, Indiana

When approaching this property from the east on I-40, this hotel is not easy to find. Shortly after exiting I-40 there is a small sign partially obstructed by a tree. The sigh reads Best Western and s... more

Owner Response
Andria K, General Manager at BEST WESTERN Santa Fe, responded to this review
Ken, I am very sorry to hear about your confusion in finding our hotel. Best Western just recently updated all of their logos so I know it can be hard finding us when looking for the new logo ! I also apologize that our front desk agent was not very helpful in the directions. She just moved to Amarillo and is still a little unfamiliar with the directions. But we will work with her on that! We are open to any of your breakfast suggestions to improve breakfast for our guests. Once again I apologize that your stay with us at the Best Western Santa Fe in Amarillo did not exceed your expectations!! I hope you give us another chance! If you need to speak with me directly regarding your stay you may call me at 806-372-1885. Or you may email me at bestwesternsantafe@yahoo.com. Have a wonderful day and I hope you choose to stay with us again! Andria Keelin

Road trip

25/09/2016 MichiganCathy, Michigan

This is a very very nice motel. From the outside it looks plain but the inside has been totally remodeled and decorated and is amazing. The beds and pillows are comfortable and the bathroom and floori... more


Way overpriced for this property

25/09/2016 Diane1154, Loveland, Colorado

Thought we have always enjoyed staying at Best Western hotels, this particular one disappointed us . It was overpriced for the area it is situated in. The lobby is small, which is also the breakfast... more